2023 Women’s Psychiatric Leadership Meeting
In-Person event
Sunday, August 27, 2023
10:30 am -1:30 pm
Champagne Brunch at the
EAST BANK CLUB
500 N Kingsbury St, Chicago, IL 60654
Onsite Parking Available
Topic: Premenstrual Mood Disorders: Advances in Epidemiology, Pathophysiology, and Treatment
Summary: Premenstrual Mood Disorders (PMDs) occupy a complex space at the intersection of biological sex and gendered experience. While most cycling individuals do not experience distressing or impairing premenstrual mood symptoms, a substantial minority experience marked changes in emotion and behavior that require medical diagnosis and treatment. Steady progress across the last 30 years has led to the establishment of the Premenstrual Dysphoric Disorder diagnosis in the DSM-5, as well as the development of a substantial empirical knowledge base regarding the epidemiology, pathophysiology, and evidence-based treatment of PMDs. In this talk, I will review critical aspects of the literature on PMDs while sharing insights from mechanistic clinical trials in my own laboratory.
REGISTRATION FOR THIS EVENT IS CLOSED!
Meet our Guest Speaker:
Tory Eisenlohr-Moul, PhD
Positions: I am an Associate Professor of Psychiatry at UIC. I am a Clinical Psychologist with specialized fellowship training in both suicide and the pathophysiology of reproductive mood disorders -- particularly premenstrual disorders. I also serve as an Associate Director of the Medical Scientist Training Program at UIC, and volunteer as the chair of the Clinical Advisory Board at a nonprofit focused on premenstrual mood disorders (International Association for Premenstrual Disorders).
Science: As a scientist, I work primarily with mechanistic randomized controlled trials (RCTs) and longitudinal observation studies to clarify how ovarian steroids alter transdiagnostic RDoC constructs (e.g., processing of loss and threat) and related phenotypes (particularly suicidality and alcohol use) in susceptible females. My NIMH-funded trials (K99/R00MH109667; RF1MH120843) examine the effects of natural changes in neuroactive steroids (vs. exogenous steroid stabilization) on transdiagnostic mechanisms of proximal suicide risk during the perimenstrual weeks of the menstrual cycle. My work in this area has provided the first evidence for the feasibility and safety of conducting experimental steroid manipulation studies in patients living with suicidal thoughts and behaviors. Results of the first trials indicate that perimenstrual hormone stabilization (particularly of estrogen) prevents the increase in depression and suicidal ideation that is observed under placebo during the perimenstrual phase. Recently, I have also been awarded collaborative grants to study the role of the menstrual cycle in (1) adolescent suicidal ideation and behavior (R01MH122446), (2) alcohol use (R21AA028736), (3) ADHD (R01MH119119), and borderline personality disorder (R01MH126940). I am passionate about training early career scientists and empowering colleagues to conduct rigorous scientific work on the menstrual cycle and mental health.
Questions? Contact Kristen Malloy at kmalloy@ilpsych.org.
This is event is Sponsored by:
